![]() Coma or brain death: Severe brain damage may cause a change in the size and reactivity of the pupils. Anisocoria indicates a difference in pupil diameter in common clinical manifestations, if anisocoria is more marked in bright light, the large pupil is.Surgery: Eye surgery may result in alterations in pupil size, which can be permanent.Seizure: Sometimes seizures (a disruption of electrical activity in the brain) can cause changes in the pupils, which may be equal or unequal.Migraine: While it is not common, migraines can cause anisocoria.Vision loss: Significant vision defects can affect pupil size and reactivity. ![]() Because pressure builds up inside the eye, both types can cause migraine-level pain. Increased intracranial pressure: This can result from a brain tumor, meningitis (inflammation of the fluid around the brain), or a stroke. If cats get glaucoma, they are more likely to have the secondary type.Trauma: An injury affecting the eye or the brain may cause the pupils to be unequal.Inflammatory conditions, such as MS and sarcoidosis, also can do this. However, there are medical reasons that cause cats’ pupils to dilate, including: Stress. Healthy eye dilation in cats happens when their pupils naturally grow larger in dim light or darkness and become narrower in bright environments. Your doctor can measure your pupils in both eyes to see how well they shrink and grow. When in a bright room or in sunlight, the pupil usually gets smaller (or constricts). Normal pupils are 2 to 4 millimeters in bright light and 4 to 8 millimeters in the dark. The size of the pupil depends on how much the iris muscle is constricted (tightened). Inflammation: An infection affecting the eye or the cranial nerves can cause anisocoria. How dilated cat eyes can signal health problems. The empty hole in the middle, which allows light to enter the eye, is called the pupil.Cranial nerve damage: This can occur due to a stroke (a blockage of blood flow or bleeding in the brain), brain aneurysm (defect in a blood vessel), or a brain tumor.Multiple sclerosis (MS): MS is a chronic neurological disorder that causes symptoms affecting vision, movement, sensation, and more. Unequal pupil size, or anisocoria, is a condition in which the pupils are different sizes at the same time.
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